Flap of the sternocephalicus muscle in the repair of a partial defect in the trachea of a rabbit (Oryctolagus cuniculus).

PURPOSE: The current study aimed at evaluating the repair of a partial defect of the trachea with a muscle flap, an advanced technique that employs combined suture patterns. METHODS: Sixteen healthy male New Zealand white rabbits were used as an experimental model. A partial defect in the trachea within the ventral region of the fourth to eighth tracheal ring was created. Subsequently, repair was initiated with a flap of the sternocephalicus muscle. The animals were divided into four groups for postoperative evaluation using clinical, tracheoscopic, and histopathological analyses. Each group was separated according to the time of euthanasia, programmed at interval of seven (G7), 15 (G15), 30 (G30), and 60 days (G60). RESULTS: One animal from the G60 group died, whereas the other animals had good surgical recovery without serious changes in the breathing pattern. The major clinical signs observed were stridor and coughing. Tracheoscopy revealed secretions in the tracheal lumen, exuberant granulation, and stenosis. Histopathological analysis showed growth of the ciliary respiratory epithelium at the flap site 30 days after implantation. CONCLUSIONS: Partial repair showed satisfactory results owing to the anatomical location of the muscle, adequate vascular support, and structural and physiological maintenance without serious changes in the respiratory system.

Flap of the sternocephalicus muscle in the repair of a partial defect in the trachea of a rabbit (Oryctolagus cuniculus)

Purpose: The current study aimed at evaluating the repair of a partial defect of the trachea with a muscle flap, an advanced technique that employs combined suture patterns. Methods: Sixteen healthy male New Zealand white rabbits were used as an experimental model. A partial defect in the trachea within the ventral region of the fourth to eighth tracheal ring was created. Subsequently, repair was initiated with a flap of the sternocephalicus muscle. The animals were divided into four groups for postoperative evaluation using clinical, tracheoscopic, and histopathological analyses. Each group was separated according to the time of euthanasia, programmed at interval of seven (G7), 15 (G15), 30 (G30), and 60 days (G60). Results: One animal from the G60 group died, whereas the other animals had good surgical recovery without serious changes in the breathing pattern. The major clinical signs observed were stridor and coughing. Tracheoscopy revealed secretions in the tracheal lumen, exuberant granulation, and stenosis. Histopathological analysis showed growth of the ciliary respiratory epithelium at the flap site 30 days after implantation. Conclusions: Partial repair showed satisfactory results owing to the anatomical location of the muscle, adequate vascular support, and structural and physiological maintenance without serious changes in the respiratory system.

Frequência de neoplasias cutâneas em cães atendidos no hospital veterinário da Universidade Federal de Uberlândia durante os anos 2000 a 2010 / Frequency of skin cancer in dogs treated at the Federal University of Uberlândia veterinary hospital from 2000 to 2010

Foram analisados os arquivos do laboratório de Patologia Animal do Hospital Veterinário da UFU de janeiro de 2000 a dezembro de 2010, selecionando protocolos referentes a biopsias cutâneas de cães coletando-se as seguintes informações: diagnóstico morfológico, localização anatômica, idade, sexo e raça dos cães, com o objetivo de realizar um estudo epidemiológico. Foram diagnosticados 549 tumores cutâneos em 543 cães, sendo que 281 cães eram machos e 247 fêmeas. Cães adultos e idosos foram os mais acometidos, assim como os cães sem raça definida, Poodle, Boxer, Pit Bull e Dashchund. Os tumores malignos prevaleceram com 65,39% dos casos, sendo os de origem epitelial os mais frequentes. O carcinoma de células escamosas foi a neoplasia predominante, seguido pelo mastocitoma e histiocitoma. Com relação á localização anatômica prevaleceu as regiões do abdômen (19,49%), cabeça (16,40%) e membros (15,30%). Não houve diferença na probabilidade de apresentar tumor cutâneo com relação ao sexo, porém considerando-se os tipos de tumores há maior probabilidade da população canina apresentar carcinoma de células escamosas e mastocitomas em detrimento dos outros tipos de tumores cutâneos.

We analyzed the archives of the Animal Pathology Laboratory of the Federal University of Uberlândia Veterinary Hospital from 2000 to 2010 with the aim of conducting an epidemiological study. Protocols for skin biopsies of dogs were selected and the following information was collected: morphological diagnosis, anatomical location, age, gender, and breed. Five hundred forty-nine skin tumors were diagnosed in 543 dogs, of which 281 were males and 247 were females. Adult and older dogs were the most affected, and mongrel dogs, Poodles, Boxers, Pit Bulls, and Dashchunds were the most frequent breeds. Malignant tumors were present in 65.39% dogs, and most tumors were derived from epithelial cells. Squamous cell carcinoma was the predominant neoplasia, followed by mast cell tumors and histiocytoma. With respect to the anatomic location, the abdomen (19.49%), head (16.40%), and limbs (15.30%) were the most frequently affected. Gender did not influence the probability of having a cutaneous tumor. With regard to tumor type, the canine population was more susceptible to squamous and mast cell tumors than to other skin tumors.

Alterações histopatológicas e macroscópicas em um cão sorologicamente positivo para Leptospira spp / Case report: Macroscopic and histopathological changes in a dog serologically positive for Leptospira spp

A leptospirose é uma zoonose de distribuição mundial com elevada incidência em regiões tropicais.Nos cães ela se apresenta com grande polimorfismo clínico e estes animais são consideradosfonte de infecção da leptospirose humana, mesmo quando não apresentam qualquer sinal clínicocaracterístico. O processo de patogênese é caracterizado pelo desenvolvimento de vasculite, lesãoendotelial e infiltrado inflamatório composto por células monocíticas, plasmócitos, histiócitos eneutrófilos. O objetivo deste estudo foi relatar o caso de um cão sorologicamente positivo paraleptospirose. Logo após o óbito, o animal foi encaminhado ao Departamento de Patologia Animaldo Hospital Veterinário da Universidade Federal de Uberlândia. Na necropsia foram diagnosticadasicterícia hemolítica e nefrite intersticial crônica moderada. As alterações macroscópicas, histológicase sorológicas do animal foram sugestivas de doença hemolítica grave compatível com leptospirose.

Leptospirosis is a zoonosis of worldwide distribution with high incidence in tropical regions.Leptospirosis in dogs presents with large clinical polymorphism and these animals are consideredsources of infection for human leptospirosis, even without showing any clinical signs. Pathogenesisis characterized by the development of vasculitis, endothelial injury and infiltration of monocyticcells, plasma cells, histiocytes and neutrophils. The objective of this study was to report the caseof a dog serologically positive for leptospirosis. The animal died and then was submitted to theAnimal Pathology Department of the Veterinary Hospital of the Federal University of Uberlândia At necropsy hemolytic jaundice and moderate chronic interstitial nephritis were diagnosed. Themacroscopic, histological and serological changes suggest severe hemolytic disease consistent withleptospirosis.